Targeted Extinction of Drug Cues During Sleep - Olfactory Cue Reactivity Task (TEDDS_OCRT)

  • participants needed
  • sponsor
    Central Institute of Mental Health, Mannheim
Updated on 2 July 2022


The study aims to utilise olfactory stimulation in addition to the visual stimulation in cue reactivity tasks to enhance precision in measuring alcohol based cues in individuals diagnosed with heavy drinking. The study consists of one cue reactivity task with visual stimuli, another cue reactivity task with matching odour/visual stimuli and lastly a monetary incentive delay task.


The intention of the study is to enhance the measurement precision in image-based cue reactivity task by introducing a new level of stimuli in the form of odours. During the course of the functional Magnetic Resonance Imaging (fMRI) screening, participants are required to finish three tasks, namely; odour-based cue reactivity task (OCRT), image-based cue reactivity task(ICRT) and monetary incentive delay task (MID).

Participants will be randomly divided into two groups, one group will receive tasks in the following order: OCRT-MID-ICRT and the other group will receive them in the following order: ICRT-MID-OCRT. With this, the habituation effect from receiving odours during OCRT is expected to be balanced.

Condition Heavy Drinking
Treatment Beer, Lavender, Orange, ROSE, Wine, Wine, Schnapps
Clinical Study IdentifierNCT05189379
SponsorCentral Institute of Mental Health, Mannheim
Last Modified on2 July 2022

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