Melatonin Use After Primary Total Joint Arthroplasty

  • participants needed
  • sponsor
    NYU Langone Health
Updated on 30 January 2023


The purpose of this study is to determine the effect of melatonin supplementation on patient sleep quality, length of stay, and opioid consumption following primary, unilateral, elective total hip or knee arthroplasty.


This will be a single-center randomized double blind placebo control clinical trial. In the cohort of patients undergoing primary elective total hip and the cohort of patients undergoing primary elective knee arthroplasty, participants are recruited from those who are willing to consent and participate in the study, and will be randomly 1:1 divided into intervention group and placebo group.

Condition Osteo Arthritis Knee
Treatment Placebo, Melatonin 5 mg
Clinical Study IdentifierNCT04795336
SponsorNYU Langone Health
Last Modified on30 January 2023

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