Parkinson's Progression Markers Initiative Online (PPMI Online)

  • End date
    Dec 7, 2041
  • participants needed
  • sponsor
    Michael J. Fox Foundation for Parkinson's Research
Updated on 14 September 2022
Online studies
Accepts healthy volunteers


Parkinson's Progression Markers Initiative Online (PPMI online) is part of the broader Parkinson’s Progression Markers Initiative aimed at better understanding who gets Parkinson’s disease and why. PPMI online is a study collecting participant reported demographic and health information online from people with and without Parkinson’s disease. Once in the study, you will answer questions related to various aspects of your health that may be related to your risk of developing Parkinson’s.

Whether you have Parkinson's or not, you are needed to find better ways to diagnose, treat, and even prevent this brain disease. This study is fully remote and currently based in the United States. PPMI is sponsored by The Michael J. Fox Foundation for Parkinson's Research. Visit to get started today.


To participate in the study, you will need an email address, and a computer or smartphone with internet access. Once you are in the study, you will begin answering questions related to various aspects of your health. These questions will apply to you whether you have been diagnosed with Parkinson’s or not. You will then receive emails every 90 days letting you know when it is time to come back and answer questions again. If you know someone with Parkinson's, you can help them answer PPMI questions, just make sure that you only input information about that person. 

While most people will never get Parkinson's, the data you contribute here online could help us understand who gets it and why.  Anyone over the age of 18 in the United States is eligible, whether you have Parkinson's or not. You are especially needed if: 

  • You have a close family member with Parkinson's OR
  • You act out your dreams while you're sleeping OR
  • You've noticed a persistent loss in your sense of smell or you have a genetic mutation linked to Parkinson's OR
  • You are a man over 60 years old

PPMI online has been designed to capture your data securely online, over time, using the internet. Depending on the information you provide, you may also be invited to answer different questions and to visit a medical clinical for additional testing. Participants in PPMI online may also be asked to participate in additional PPMI studies as they are developed. 

The study is expected to continue for several years. The longer you continue to contribute data, the more value you can add to the study. As a study participant, you will be kept informed over time of the scientific results you are helping researchers to generate. PPMI online is currently taking place in the United States but will soon expand to other countries. If you have questions about this study, please email our team at or call 877-525-PPMI. 

Condition Parkinson Disease, parkinson's disease, Parkinson's Disease
Treatment Observation
Clinical Study IdentifierNCT05065060
SponsorMichael J. Fox Foundation for Parkinson's Research
Last Modified on14 September 2022


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Inclusion Criteria

_ People with or without Parkinson's Disease
Age 18 years or older
Living in the United States
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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