Updated on 1 February 2022


A Phase 2, Randomized, Double-Blind, Placebo and Active Comparator-Controlled Study to Assess Efficacy and Safety of Multiple Dose Levels of AZD5718 Given Orally Once Daily for Twelve Weeks in Adults with Moderate-to-Severe Uncontrolled Asthma.


  • Condition: Asthma
  • Clinical Trial Identifier: N/A
  • Sponsor: AstraZeneca

Condition Asthma
Clinical Study IdentifierTX291177
Last Modified on1 February 2022


Yes No Not Sure

Inclusion Criteria

be 18 to 55 years of age
have moderate to severe uncontrolled asthma
have documented diagnosis of asthma 12 months prior to screening visit

Exclusion Criteria

A severe asthma exacerbation within 8 weeks of randomization
Participants with a significant COVID-19 illness within 6 months of enrollment
Participants with a diagnosis of COVID-19 pneumonia based on radiological assessment
Participants with a diagnosis of COVID-19 requiring hospitalization and/or oxygen supplementation therapy
Galactose intolerance, Lapp lactase deficiency, or glucose-galactose metabolism
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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