DLSCT for Breast Cancer Detection in Women With Dense Breasts (DECREAS)

  • STATUS
    Recruiting
  • End date
    Jan 1, 2023
  • participants needed
    14
  • sponsor
    Rijnstate Hospital
Updated on 23 March 2022
mammogram

Summary

The main objective of this project is to demonstrate the feasibility of DLSCT to detect breast cancer in women with dense breasts.

Patients with locoregional advanced primary breast cancer and heterogeneously (n = 7) or extremely dense breasts (n = 7) as determined by mammography will be included in this study. These patients have an indication for a positron emission tomography computed tomography (PET-CT) scan to search for distant metastases. In this study the participants will undergo an additional contrast enhanced DLSCT scan to determine the feasibility of spectral CT to detect breast cancer in women with dense breasts.

Details
Condition Breast Neoplasms, Breast Density, Radiographic Image Interpretation, Computer-Assisted
Treatment Dual-layer spectral computerized tomography (DLSCT)
Clinical Study IdentifierNCT05181059
SponsorRijnstate Hospital
Last Modified on23 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

Diagnosis of histopathologically proven locoregional advanced primary breast cancer
Tumors > 5 cm (= T3) or
Tumors with invasion of the skin or chest wall (= T4) or
Any tumor with ≥ 4 axillary lymph nodes or ipsilateral internal mammary, infraclavicular or supraclavicular nodal involvement (= N2-3)
Heterogeneously or extremely dense breasts as described by visual assessment on
full-field digital mammograms: category C or D according to the ACR BI-RADS
lexicon

Exclusion Criteria

History of allergic reactions to iodinated contrast agents
Pregnancy or breast feeding
Treatment of thyroid disease with radioactive iodine
Use of metformin
Creatinine clearance < 45 ml/min
Chronic or acutely worsening renal disease
Patients who are declared incompetent
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note