Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation

  • End date
    Jul 30, 2033
  • participants needed
  • sponsor
    Zhongshan Ophthalmic Center, Sun Yat-sen University
Updated on 21 March 2022


To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia


Treatment of pediatric cataract, one of the leading causes of childhood blindness globally, remains challenging because of extremely high incidence of glaucoma-related adverse events (AEs) after IOL implantation. The investigators aim to compare the incidence of glaucoma-related AEs of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia.

Condition Lens Implantation, Intraocular
Treatment Secondary in-the-bag IOL fixation, Secondary ciliary sulcus IOL fixation
Clinical Study IdentifierNCT05136950
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Last Modified on21 March 2022


Yes No Not Sure

Inclusion Criteria

Aged between 18 months and 14 years
Had a primary diagnosis of congenital cataract
Underwent cataract extraction between the ages of 2 and 24 months

Exclusion Criteria

Primary IOL implantation
Pre-existing ocular disease which might affect the location and outcome of secondary IOL implantation (including and not restricted to microphthalmia, microcornea, microcornea, corneal opacity, pseudopterygium, iris anomaly, glaucoma diagnosed before cataract extraction, uveitis, persistent fetal vasculature or trauma)
Suture fixation for secondary IOL implantation
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