PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

  • End date
    Jan 31, 2039
  • participants needed
  • sponsor
    Seattle Children's Hospital
Updated on 7 October 2022
cell transplantation


A phase 1, open-label, non-randomized study enrolling pediatric and young adult patients with relapsed or refractory CD33+ leukemia with and without prior history of allogeneic hematopoietic cell transplantation, to examine the safety and feasibility of administering an autologous T cell product that has been genetically modified to express a Dimerizing Agent Regulated Immunoreceptor Complex (DARIC).

Condition Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse
Treatment SC-DARIC33
Clinical Study IdentifierNCT05105152
SponsorSeattle Children's Hospital
Last Modified on7 October 2022


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