Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility

  • STATUS
    Recruiting
  • End date
    Jul 1, 2024
  • participants needed
    70
  • sponsor
    Instituto Dante Pazzanese de Cardiologia
Updated on 26 March 2022

Summary

The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance Image (MRI) can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months.

Description

The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months and through the improvement in segmental contractility of infarcted related artery at MRI.

Details
Condition STEMI - ST Elevation Myocardial Infarction, Myocardial Dysfunction, Percutaneous Coronary Intervention
Treatment Optimized Medical Treatment (OMT), Drug Eluting Stent (DES) Coronary Angioplasty
Clinical Study IdentifierNCT05160311
SponsorInstituto Dante Pazzanese de Cardiologia
Last Modified on26 March 2022

Eligibility

Yes No Not Sure

Inclusion Criteria

STEMI not reperfused between 24 hours and 28 days
MI-related artery with > or = 50%
Segmental dysfunction in the artery related to infarction
Technical feasibility for PCI recanalization
Absence of Myocardial Viability

Exclusion Criteria

Age > 80 years
< 1 year life expectancy
Post MI Angina
Clinical Instability
Electrical Instability
Previous Infarction with segment disfunction
New York Heart Association (NYHA) class III or IV of heart failure
Previous diagnosis of congestive heart failure or cardiomyopathy
Severe heart valve disease
Absence of segmental dysfunction in the artery related to infarction
Coronary angiography without obstructive lesions
Indication of myocardial revascularization surgery
Opted for clinical treatment for technical reasons
Serum creatinine concentration greater than 2.5 mg/dl
Pacemaker or Implantable Cardiodefibrillator (ICD)
Brain Clip Carriers
Patients with Cochlear Implants
Refusal to sign the Informed Consent Form (ICF)
Inability to maintain outpatient follow-up for 6 months
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