Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function.

  • STATUS
    Recruiting
  • days left to enroll
    18
  • participants needed
    80
  • sponsor
    Gangnam Severance Hospital
Updated on 27 August 2023

Summary

Investigators will examaine the effects of Analgesia Nociception Index (ANI)-guided analgesia on postoperative bowel function recovery in laparoscopic colorectal surgery. This is a prospective randomized-controlled study.

Investigators will randomly divide the patients into two groups. In ANI group, remifentanil infusion rate during anesthesia will be adjusted according to ANI monitoring. In Control group, remifentanil infusion rate during anesthesia will be adjusted according to the conventional method of blood pressure and heart rate monitroing. And Investigators will evalualte the bowel function recovery in both groups after surgery, and compare between the two groups.

Details
Condition Postoperative Bowel Function Recovery
Treatment Control, ANI
Clinical Study IdentifierNCT05122078
SponsorGangnam Severance Hospital
Last Modified on27 August 2023

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients over 19 years who undergo laparoscopic colorectal surgery for colorectal cancer at Gangnam Severance Hospital, Seoul, South Korea

Exclusion Criteria

Emergency surgery
Patients undergoing colostomy
Patients with history of open abdominal surgery
Patients with arrhythmia
Patients with pacemaker insertion
Patients with history of heart transplantation
Patients taking medications that may affect ANI (antimuscarinics, alpha-agonists, beta blockers)
Patients with chronic opioid medication
Cognitive impairment
Unable to read consent form (eg illiterate, foreigner, etc.)
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