Last updated on October 2005

The Canadian Prevention of Renal and Cardiovascular Endpoints Trial

Are you eligible to participate in this study?

You may be eligible for this study if you meet the following criteria:

  • Conditions: Chronic Kidney Disease
  • Age: Between 40 - 75 Years
  • Gender: Male or Female
  • Other:
    Stratum 1 (expected about 50% of trial subjects): Diabetes mellitus (by clinical
    history with documented prior plasma glucose levels in the diabetic range, or on
    hypoglycemic medications) and CKD as documented by calculated (Cockroft-Gault
    equation) creatinine clearance between 25 and 60 mls/min/1.73m2 derived from the
    creening serum creatinine value and the next most recent known value from more than
    2 weeks prior; OR
    Stratum 2 (expected about 20% of trial subjects): Non-diabetic with CKD as defined for
    Stratum 1 and proteinuria of > 1g/L by dipstick in random urine at screening; OR
    Stratum 3 (expected about 30% of trial subjects): Non-diabetic with CKD as defined for
    tratum 1, but without proteinuria as for stratum 2 at screening

You may not be eligible for this study if the following are true:

  • Unwilling to provide informed consent
    Likely to die of any known existing disease within 6 months
    Recently unstable/advanced cardiovascular disease (MI or acute coronary syndrome,
    hospitalized heart failure, TIA or stroke, leg amputation or gangrene in past 6
    Currently receiving active treatment for a malignant, neoplastic disease other than
    localized non-melanoma skin cancer
    Progressive kidney disease currently treated by immunotherapy
    Currently receiving dialysis or likely to do so within 6 months
    Current organ transplant recipient (or planned within 6 months)
    Currently receiving ongoing care for CKD, or cardiovascular disease, in a multiple
    intervention, disease management program.
    Currently enrolled in another interventional trial
    Residing in a location not amenable to follow up for the trial

Recruitment Status: Open

Brief Description Eligibility Contact Research Team

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