The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.
Condition | Obstructive Sleep Apnea Syndrome |
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Treatment | Functional Magnetic Resonance Imaging |
Clinical Study Identifier | NCT05147649 |
Sponsor | CHU de Reims |
Last Modified on | 26 May 2022 |
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