Bacteriotherapy to Improve Underarm Odor

  • End date
    Dec 30, 2022
  • participants needed
  • sponsor
    University Ghent
Updated on 6 December 2021
Accepts healthy volunteers


The goal is to improve the underarm odor by changing the microbiome. The autochthonous bacterial community is replaced by a non-smelling microbiome, by daily application of bacteria in a spray.


Participants are recruited and selected based on their initial underarm odor and underarm microbiome. The participants use two sprays: one spray containing the bacteria, and the other nothing (placebo). Participants do not know which spray they have. They use one spray during one month, and meanwhile take samples of their underarm microbiome (for sequencing), volatome (for GC/MS analysis) and odor (for odor panel analysis). Samples are stored in the freezer and brought to the university after one month, when they receive the second spray. The bacterial spray contains bacteria that are correlated with good underarm odor.

Condition Bromhidrosis
Treatment Bacterial spray
Clinical Study IdentifierNCT03967470
SponsorUniversity Ghent
Last Modified on6 December 2021


Yes No Not Sure

Inclusion Criteria

above average underarm malodor
microbiome dominated with malodorous bacteria

Exclusion Criteria

not healthy
microbiome with too high levels of Staphylococcus
Clear my responses

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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