Infant Modified Constraint Induced Movement Therapy Paired With Neuromuscular Electrical Stimulation: a Case Series

  • STATUS
    Recruiting
  • End date
    May 15, 2023
  • participants needed
    5
  • sponsor
    Kathy Grinde
Updated on 3 December 2021
movement therapy

Summary

This study will compare the motor outcomes for five infants with asymmetrical hand function (AHF) who will receive two, three week episodes of standard care separated by a three week episode of mCIMT paired with Neuromuscular Electrical Stimulation. The results of this study will inform decisions on the feasibility and efficacy of the treatment for use in a larger study for infants with AHF at risk for unilateral cerebral palsy.

Description

Infants with asymmetrical hand function will participate in three consecutive phases of treatment.

The first and third phase will consist of three weeks of standard care for children with asymmetrical hand function, 1 hour/day, 1 day/week. The therapist will provide weekly coaching with the parents so they can carry over activities at home one hour/day, six days/week during this phase. In addition, a sock or mitten will be used for short term constraint during the hour of training both in the clinic with the therapist and at home with the parent.

The second phase will consist of three weeks of modified constraint induced movement therapy, 2 hours/day, 3 days/week paired with NMES, 15 minutes/day, 3 days/week. The infants will wear a soft splint on their preferred hand and forearm 24 hours/day during this phase. Parents will be trained by the therapist to carry over activities with their child at home, 1 hour/day, 6 days/week.

The children will return at chronological age of 18 months for follow up testing.

Details
Condition Cerebral Palsy (Pediatric), Unilateral Cerebral Palsy, Cerebral Palsy, cerebral palsy (cp), Hemiplegia
Treatment Neuromuscular electrical stimulation, Modified Constraint Induced Movement Therapy, Standard care for infant with asymmetrical hand function
Clinical Study IdentifierNCT05134272
SponsorKathy Grinde
Last Modified on3 December 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Infant is 7-10 months of age (CCA)
Clinical presentation of asymmetrical hand function
Grade 2/5 movement in more impaired upper extremity
Demonstrate potential to participate in 6 hours of therapy/week during 3 week episode of mCIMT-NMES, as determined by principal investigator
Parent/guardian willing to be partners in study and participate in follow-up assessments until child is 18 months of age

Exclusion Criteria

Medical or sensory condition that prevents full therapy participation (active seizures, significant visual impairment)
Received Botox injection to more impaired upper extremity within last 6 months
NMES contraindicated (impaired skin integrity, presence of pacemaker, clotting disorder)
Previous UE surgery or nerve injury (brachial plexus)
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