Xenon-enhanced Ventilation CT-guided Radiotherapy for Lung Cancer Treatment

  • STATUS
    Recruiting
  • End date
    Dec 31, 2024
  • participants needed
    60
  • sponsor
    National Taiwan University Hospital
Updated on 2 December 2021
cancer
lung cancer
assisted ventilation
lung carcinoma

Summary

The investigators aim to use xenon-enhanced ventilation computed tomography (CT) to design personalized functional lung avoidance radiotherapy for lung cancer patients who are scheduled to receive lung radiation therapy. The investigators' goal is to optimally protect the lung function of the patients and reduce the incidence of radiation pneumonitis.

Description

There has been an increase in the application of radiation therapy in the treatment of lung tumors; however, the associated side effect, called radiation pneumonitis, can significantly reduce lung function and the quality of life of patients, eventually leading to fatal consequences. The investigators aim to use xenon-enhanced ventilation computed tomography (CT) to design personalized functional lung avoidance radiotherapy for lung cancer patients who are scheduled to receive lung radiation therapy. The investigators' goal is to optimally protect the lung function of the patients and reduce the incidence of radiation pneumonitis.

Details
Condition Bronchial Neoplasm, lung carcinoma, Pulmonary Disease, Lung Disease, carcinoma lung, Lung Neoplasm, Lung Cancer, Radiation Therapy Complication
Treatment Xenon-enhanced Ventilation CT-guided Radiotherapy
Clinical Study IdentifierNCT05134558
SponsorNational Taiwan University Hospital
Last Modified on2 December 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients aged 20-80 years, with lung cancer receiving thoracic radiotherapy in NTUH, from February 2020 to December 2024

Exclusion Criteria

The age is less than 20 years old or older than 80 years old
Unstable clinical condition, unable to maintain apnea for 15 second, and history of prior adverse reaction to xenon
Renal insufficiency patients
Claustrophobia
Those who are pregnant
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