Force Sensing Resistor for Obstructive Sleep Apnea Patients After Tongue Base Reduction Surgery

  • STATUS
    Recruiting
  • End date
    Dec 31, 2022
  • participants needed
    104
  • sponsor
    National Cheng-Kung University Hospital
Updated on 2 December 2021

Summary

Obstructive sleep apnea syndrome (OSA) is a sleep-related breathing disorder defined by repetitive episodes of apnea and hypopnea. These traits include anatomical (narrow/crowded/collapsible upper airway) and nonanatomical (waking up too easily during airway narrowing [a low respiratory arousal threshold], ineffective or reduced pharyngeal dilator muscle activity during sleep, and unstable ventilatory control [high loop gain]) components. Oropharyngeal training reduces the snoring times, Apnea-hypopnea Index (AHI) and daytime sleepiness. There is lack of good evaluating tools to distinguish different phenotypes of OSA and the efficacy of combined therapy. The purposes of our study are (1) to evaluate OSA patient by using Polysomonogrphy (PSG), force sensing resistor (FRS), Drug induce sleep endoscopy (DISE) and CT and muscle strength testing, (2) to know the exercise times by using FSR and (3) the efficacy of exercise in different groups.

Description

Subjects who are newly diagnosed with mild to severe OSA (AHI >5/h), and the physician will explain the treatment programs to every subject. By the result of muscle strength testing, the subjects will be classified as low muscle strength and normal groups. The myofunctional therapy program will begin at 6 week after surgery, and subjects will undergo 12 weeks of the home-based oropharyngeal myofunctional therapeutic training. During the training intervention period, subjects will be interviewed one time per week for adjusting the treatment intensity.

Expected resultsThe hypothesis of this study is the efficacy of exercise would be less in the low muscle strength OSA patient than normal.

Details
Condition Obstructive sleep apnea
Treatment Tongue base reduction surgery
Clinical Study IdentifierNCT05133011
SponsorNational Cheng-Kung University Hospital
Last Modified on2 December 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Clinical diagnosis of mild to severe OSA in the past year
Agree to receive Transoral Robotic Surgery (TORS)
Age between 20-65 years old

Exclusion Criteria

Body Mass Index 32
Drug abuse within one year
Pregnant
Severe obstructive or restrictive lung disease
A history of malignancy or infection of the head and neck region and laryngeal trauma
Craniofacial malformation
Stroke
Neuromuscular disease
Heart failure
Coronary artery disease
Ongoing or uncontrolled chronic diseases
Combine central or mixed types sleep apnea syndrome
Other non-breath related sleep disorder
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