Improving Prospective Memory Via Telehealth

  • End date
    Oct 31, 2022
  • participants needed
  • sponsor
    Saint Francis Care
Updated on 28 November 2021
cognitive rehabilitation


Up to 70% of persons with multiple sclerosis (PwMS) experience cognitive impairment, which can have a significant impact on several aspects of their daily lives. One cognitive domain that has been shown to impact daily functioning, but is understudied in MS, is prospective memory (PM). While there have been successful PM interventions in other clinical populations, to date there has not been a specific PM intervention for PwMS that has been tested in a clinical trial.

The study will be a double-masked randomized feasibility trial, with 18 participants randomized to a PM intervention and 18 participants randomized to an active control (psychoeducation). Participants will meet with an interventionist twice a week for four weeks. Feasibility will be assessed via 1) recruitment, enrollment, and retention; 2) adherence to the treatment; 3) treatment credibility and expectancy; and 4) treatment satisfaction. A preliminary effect size (Cohen's d) will be computed for the group difference using participants' performance on the Memory for Intentions Test, which will be given at baseline (week 1) and post-treatment (week 6). Participants will also complete a battery of neuropsychological measures as part of their baseline and post-treatment assessments.

Condition Multiple Sclerosis, multiple sclerosis (ms), Dermatite Atopique modérée ou grave, Radiologically Isolated Syndrome
Treatment Educational, Prospective Memory Intervention
Clinical Study IdentifierNCT05129293
SponsorSaint Francis Care
Last Modified on28 November 2021


Yes No Not Sure

Inclusion Criteria

Clinical diagnosis of MS
Able to read, write, and speak in English
Between the ages of 18 and 60
All genders
No history of other serious neurologic or psychiatric illness, including drug or alcohol misuse
No relapses within the past two months
Access to the Internet and a web camera
Not enrolled in a cognitive rehabilitation program within the past six months
Self-reported issues "remembering places they have to be" and "things they have to do

Exclusion Criteria

No diagnosis of MS
Unable to complete the study protocol due to language barriers
Younger than 18 or older than 61
No gender exclusions
History of other serious neurologic or psychiatric illness, including drug or alcohol misuse
Had a relapse within the past two months
No access to the Internet and/or a web camera
Currently enrolled or enrolled in a cognitive rehabilitation program within the past six months
No self-reported issues with "remembering places they have to be" or "things they have to do
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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