ProspectIve Cohort psoriASiS fOllow-up (PICASSO)

  • End date
    Oct 19, 2032
  • participants needed
  • sponsor
    Universitaire Ziekenhuizen Leuven
Updated on 12 December 2021


The main purpose of the PICASSO-project is to facilitate future psoriasis-research in dermatology. This register biobank will enable us to perform research in the field of metabolomics, mRNA-expression, cardiovascular impact and the microbiome. The final aims are patient stratification, better insight in disease-evolution and improved understanding of markers that predispose to severe disease.


The PICASSO-project is a prospective register with extensive biobanking in which patients with a recent onset of psoriasis (<3 years) can be enrolled. Participants are followed for a period of 10 years, with scheduled visits every 2.5 years. The same protocol is followed for every visit. The registry captures patient demographics, medical history (personal and family), details of psoriasis treatment (previous and current), physical examination, disease activity scores and PROMs. Some patients (substudy) will undergo ultra-sound to determine carotid intima media thickness. Biobanking in this project encompasses extensive biosampling of multiple tissues. It is not within the scope of this project to administer study medication: patients receive standard of care treatment as prescribed by their physician.

Condition Psoriasis
Clinical Study IdentifierNCT05122039
SponsorUniversitaire Ziekenhuizen Leuven
Last Modified on12 December 2021


Yes No Not Sure

Inclusion Criteria

Clinical signs of Psoriasis since >3 years
adults (70 years old or less) and children (>12 years old)
willing and able to understand and sign the informed consent (plus legal representative in case of a minor)

Exclusion Criteria

unwilling or unable to understand and sign the informed consent
disease duration longer than 3 years
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How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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