Effect of Extubation on Respiratory Function

  • STATUS
    Recruiting
  • End date
    Apr 22, 2022
  • participants needed
    34
  • sponsor
    Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Updated on 22 November 2021

Summary

The extubation phase is a risky period of anesthesia management. During this step, serious complications can arise: hypoxemia, laryngospasm, pharyngeal obstruction, pneumonia In spite of these complications, extubation and its impact on respiratory function, particularly on the Functional Residual Capacity (FRC), remains poorly studied because of the difficulty to make bedside measurements.

The PulmoVista 500 is a clinical routine which provide effective non-invasive bedside measurements. It would be interesting to evaluate the impact of extubation on respiratory function, and more specifically FRC changes during and after extubation.

This study will allow a better physiopathological knowledge and a quality improvement patient extubation management.

Description

The aim of this study is to evaluate the variation of functional residual capacity and its distribution before and after extubation.

Patients with scheduled surgery and receiving general anesthesia with orotracheal intubation are included and the measurements will be performed in the post-interventional monitoring room (PICU). EELI data will be collected before extubation and then at T0, then T5, T10, T15 and T20 minutes. No subsequent follow-up is required.

Details
Condition Functional Residual Capacity
Treatment Functional residual capacity measure by electrical impedance tomography
Clinical Study IdentifierNCT05077605
SponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Last Modified on22 November 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patient over 18 years
Patient in operating room for scheduled surgery
Patient receiving general anaesthesia with orotracheal intubation
Patient given written consent after information
Patient covered by social security or equivalent regimen

Exclusion Criteria

Patient undergoing thoracic and spinal surgery, due to the presence of dressings that interfere with measurements
Patient who has undergone intracerebral surgery because of possible communication difficulties upon awakening
Patients with a body mass index (BMI) > 50 (measurements not possible)
Pregnant or breastfeeding patient
Patient contraindicated to the use of a thoracic electroimpedancemetry technique: dressings, wounds, presence of a pacemaker, defibrillator or any other active implant
Patient deprived of liberty by a judicial or administrative decision or patient subject to a legal protection measure (guardianship, curatorship...)
Patient in a period of exclusion from another research protocol
Any other reason that, in the opinion of the investigator, could interfere with the evaluation of study objectives
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