Surgical Treatment of a Chronic Anal Fissure

  • End date
    May 1, 2023
  • participants needed
  • sponsor
    State Scientific Centre of Coloproctology, Russian Federation
Updated on 18 November 2021


This study is aimed at studying the effectiveness and safety of surgical treatment of chronic anal fissure.


A chronic anal fissure is a rupture of the mucous membrane of the anal canal, lasting more than 2 months and resistant to non-surgical treatment. This condition is accompanied by a strong pain syndrome during and after defecation (defecation). This condition is most often found in young and able-bodied adults, so the issue of treatment is of particular relevance.

The main cause of the development of a chronic anal fissure is a spasm of the internal sphincter. It should be eliminated first of all to ensure effective therapy.The investigators plan to treat a chronic anal fissure by performing a lateral subcutaneous sphincterotomy, without excision of the fissure.

Condition Chronic Anal Fissure
Treatment lateral subcutaneous sphincterotomy
Clinical Study IdentifierNCT05117697
SponsorState Scientific Centre of Coloproctology, Russian Federation
Last Modified on18 November 2021


Yes No Not Sure

Inclusion Criteria

Patients with chronic anal fissure

Exclusion Criteria

Inflammatory diseases of the colon
Previous surgical interventions on the anal canal
IV grade internal and external hemorrhoids
Rectal fistula
Severe somatic diseases at the decompensation stage
Pregnancy and lactation
Anal sphincter insufficiency
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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