Intervention to Improve HIV Care Retention by Addressing Stigma Stigmatized Environments

  • End date
    Nov 1, 2024
  • participants needed
  • sponsor
    University of Connecticut
Updated on 16 November 2021


Retention in care and persistent adherence to antiretroviral therapy are necessary for the successful treatment of HIV infection. HIV-related stigma is a known impediment to the care and health outcomes of people living with HIV. The proposed study will test theory-based interventions designed to manage HIV stigma in order to improve care retention and medication adherence in communities with high-levels of HIV-related stigma.


This trial is conducting a randomized test of a behavioral self-management intervention designed to improve HIV treatment outcomes in people living with HIV in stigmatized contexts. The trial includes a control arm and a non-stigma enhanced treatment adherence intervention arm. Participants living in an economically under-resourced area of South Africa are recruited through clinical care settings. The goal of the research is to examine whether directly addressing HIV stigma and medication adherence management improves treatment outcomes beyond those observed from a standard behavioral intervention without added stigma-addressing components.

Condition HIV I Infection
Treatment Uniform Standard of Care Counseling, Behavioral Self-Regulation Skills Counseling, Behavioral Self-Regulation Skills Counseling + Stigma Management
Clinical Study IdentifierNCT05110963
SponsorUniversity of Connecticut
Last Modified on16 November 2021


Yes No Not Sure

Inclusion Criteria

18 years of age or older
current clinic visit to receive cART in differentiated care outside of an adherence club
unsuppressed HIV at the most recent clinical testing confirmed in run-in
access to a phone

Exclusion Criteria

Not meeting inclusion
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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