Protective Effect of Beraprost Sodium Tablets on Reperfusion Therapy for Acute STEMI

  • End date
    Jun 30, 2023
  • participants needed
  • sponsor
    Shenzhen People's Hospital
Updated on 24 March 2022


Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction

Condition Essential Hypertension
Treatment Beraprost Sodium Tablets
Clinical Study IdentifierNCT05103813
SponsorShenzhen People's Hospital
Last Modified on24 March 2022


Yes No Not Sure

Inclusion Criteria

It meets the diagnostic criteria of acute ST segment elevation myocardial infarction: ischemic chest pain lasts for more than 30 minutes and can not be relieved by taking nitroglycerin; ST segment elevation of ECG with two or more adjacent leads, limb lead ≥ 1mm, chest lead ≥ 2mm; Or new left bundle branch block; The serum markers of myocardial necrosis increased at least twice the normal value
Acute myocardial infarction was confirmed by coronary angiography
The clinical and angiographic data were complete
Direct PCI was performed within 12 hours after onset

Exclusion Criteria

Those who do not cooperate in the inspection, have poor compliance and cannot guarantee the completion of the test
Conscious disorder, obvious intellectual disorder and mental disorder
With metal foreign bodies, such as metal prosthesis, intraocular metal foreign bodies, intracranial aneurysm clamp, etc
People with claustrophobia
Had a history of myocardial infarction, PCI and coronary artery bypass grafting
Factors affecting ST segment changes of ECG: complete left bundle branch block, preexcitation syndrome, pacemaker ECG, etc
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