Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis (DIFFEREN-STAD)

    Not Recruiting
  • days left to enroll
  • participants needed
  • sponsor
Updated on 13 May 2022
skin biopsy
Accepts healthy volunteers


Primary Objective:

  • Assess change in neuronal architecture following long term treatment with dupilumab in skin biopsies from atopic dermatitis (AD) participants with chronic pruritus

Secondary Objectives:

  • Assess change in neuronal architecture following short term treatment with dupilumab and during follow-up in skin biopsies from AD participants with chronic pruritus
  • To evaluate the efficacy of dupilumab in AD participants with chronic pruritus
  • To evaluate the safety of dupilumab in adult participants with moderate-to-severe AD


AD patients: A 20-week Observation Period including 16 weeks of treatment for AD participants and a 4-week follow-up period Healthy subjects: 8 days observation period

Condition Dermatitis Atopic
Treatment Dupilumab SAR231893
Clinical Study IdentifierNCT04823130
Last Modified on13 May 2022

Similar trials to consider


Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 



Reply by • Private

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note