Low-cost Imaging Technology for Global Prevention of Cervical Cancer

  • End date
    Dec 3, 2025
  • participants needed
  • sponsor
    Barretos Cancer Hospital
Updated on 23 October 2021
prevention of cervical cancer


Cervical cancer remains the first or second leading cause of cancer death among women in many low-and middle-income countries. Cervical cancer prevention programs in low-resource settings are hampered by a lack of personnel with appropriate clinical expertise, lack of pathology services, and lack of associated infrastructure. There is an urgent need for appropriate diagnostic tools to enable accurate screening and diagnosis in low-resource settings. The purpose of this study is to develop and validate a low-cost Multimodal Mobile Colposcope (MMC) for global cervical cancer prevention programs. This new device will combine the imaging capabilities of a mobile colposcope with the microscopic imaging capabilities of a fiber-optic confocal imaging probe.

Condition cervical intraepithelial neoplasms, Cervical Intraepithelial Neoplasia
Treatment Multimodal Mobile Colposcope (MMC)
Clinical Study IdentifierNCT05078528
SponsorBarretos Cancer Hospital
Last Modified on23 October 2021


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Inclusion Criteria

Women >25 years of age
Women undergoing colposcopy due to abnormal cervical screening or follow-up for a history of dysplasia
Women of childbearing potential must have a negative urine or blood pregnancy test
Ability to understand and willingness to provide informed consent by signing specific Informed Consent Document

Exclusion Criteria

Women under 25 years of age
Women who have undergone hysterectomy with removal of the cervix
Women with known allergy to proflavine or acriflavine
Women who are pregnant or nursing at the time of enrollment
Incapacitated women or in vulnerable situations or who are not willing to give consent
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