Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11) (KEYNOTE-C11)

    Not Recruiting
  • End date
    May 18, 2027
  • participants needed
  • sponsor
    Merck Sharp & Dohme LLC
Updated on 20 July 2022


The purpose of this study is to evaluate the safety and efficacy of pembrolizumab (MK-3475) monotherapy, followed by chemotherapy, followed by pembrolizumab consolidation. The primary hypothesis of the study is that the complete response (CR) rate at the end of study intervention according to Lugano 2014 response criteria is higher than conventional chemotherapy.

Condition Classical Hodgkin Lymphoma
Treatment cyclophosphamide, etoposide, prednisone, Pembrolizumab, Bleomycin, vincristine, doxorubicin, dacarbazine, procarbazine, Vinblastine
Clinical Study IdentifierNCT05008224
SponsorMerck Sharp & Dohme LLC
Last Modified on20 July 2022

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