Comparison of an Opioid-Free Anesthesia Protocol Versus Standard Practices on Early and Late Post-operative Recovery

  • STATUS
    Recruiting
  • participants needed
    140
  • sponsor
    University Hospital, Angers
Updated on 5 June 2023
analgesics
morphine
ketamine
opioid
remifentanil
sufentanil
lidocaine

Summary

Opioid-Free Anesthesia (OFA) is an anesthesia protocol that does not use morphine, and is increasingly used routinely. Indeed, this protocol would theoretically allow a better post-operative analgesic control, a lower incidence of post-operative complications (e.g. post-operative nausea and vomiting). In the end, it would also allow a better overall post-operative recovery and a decrease in the incidence of chronic post-operative pain.

Nevertheless, the literature is poor on this issue and no randomized controlled study has evaluated the effect of the use of this type of anesthesia protocol on postoperative recovery.

Details
Condition sensory loss, anaesthesia, Anesthesia, Opioid Analgesic Adverse Reaction, anesthesia procedures, dental anesthesia, anesthesia for, Anesthesia; Adverse Effect, Postoperative Complication, Anesthesia (Local)
Treatment Opioid Free Anaesthesia protocol, standard practice protocol based on the use of opioids (sufentanil or remifentanil)
Clinical Study IdentifierNCT04797312
SponsorUniversity Hospital, Angers
Last Modified on5 June 2023

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