Postoperative Pain Control in Total Shoulder Arthroplasty

  • STATUS
    Recruiting
  • End date
    Jul 1, 2023
  • participants needed
    150
  • sponsor
    Scripps Clinic
Updated on 15 October 2021
Accepts healthy volunteers

Summary

A double blind, prospective, randomized trial to evaluate postoperative pain, narcotic use, patient satisfaction, and function among shoulder arthroplasty patients receiving interscalene block with and without the addition of liposomal bupivacaine.

Description

In order to reduce narcotic abuse potential, orthopaedic surgeons have explored multimodal pain regimens in addition to regional anesthesia to improve postoperative pain control. One commonly used intervention to reduce postoperative shoulder pain has been the interscalene brachial plexus block. This block provides significant pain relief for shoulder procedures, but has been limited to less than 24 hours even with long acting anesthetics. In the setting of shoulder arthroplasty, this short-term pain control often leads to the need for increased narcotic pain medication. Since shoulder arthroplasty has been steadily increasing in the United States with an annual growth rate of 10.6%, it is imperative to control patients' postoperative pain without increasing their risk for opiate abuse. A potential method for achieving this is by using liposomal bupivacaine in the interscalene blocks.

This study is a double blind, prospective, randomized trial to evaluate the postoperative pain profiles among shoulder arthroplasty patients receiving interscalene block with and without the addition of liposomal bupivacaine. The purpose of this study is to determine if patients undergoing shoulder arthroplasty with an interscalene brachial plexus block with liposomal bupivacaine (study group) or without liposomal bupivacaine (control group) will have differences in postoperative opiate consumption, patient-reported pain, satisfaction with surgery, and shoulder function.

Details
Condition total shoulder replacement, Total Shoulder Arthroplasty
Treatment Liposomal bupivacaine, Bupivacaine
Clinical Study IdentifierNCT05068960
SponsorScripps Clinic
Last Modified on15 October 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients undergoing primary shoulder arthroplasty or reverse shoulder
arthroplasty

Exclusion Criteria

Patients under the age of 50 years
Patients over the age of 85
Patients undergoing a revision shoulder procedure
Documented drug or alcohol abuse
Active narcotic use within 3 months prior to surgery
Neurological deficit
Allergy to amide anesthetics
Oxycodone intolerance
Unable to take Celebrex
Enrollment in another clinical trial
Comorbidity that is contraindicated with the administration of an interscalene block
Cognitive or mental health status that interferes with study
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