Pyrexia Management Using an IL-6 Antibody in BRAF+ Melanoma Patients Treated With Dabrafenib/ Trametinib +/- Immunotherapy

  • participants needed
  • sponsor
    University of Zurich
Updated on 27 November 2022
persistent fever


The study examines the development of fever after administration of Actemra (tocilizumab) in patients who have fever and other cytokine release symptoms (headache, nausea, palpitations, low blood pressure) due to cancer therapy (Tafinlar (dabrafenib) / Mekinist (trametinib) +/- immunotherapy) . The goal of the study is to better understand the side effects and to find an effective therapy against them.

Condition Fever, fevers, pyrexia, hyperthermia
Treatment Actemra, Actemra
Clinical Study IdentifierNCT04652258
SponsorUniversity of Zurich
Last Modified on27 November 2022

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