NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

  • participants needed
  • sponsor
    NFlection Therapeutics, Inc.
Updated on 30 March 2023


This is a randomized, double-blind, vehicle-controlled, parallel group dose response study evaluating the safety and effectiveness of 2 concentrations of NFX-179 Gel in subjects with cutaneous neurofibromas. At Visit 1, the investigator will identify 10 Target cNFs that fulfil the enrollment criteria. The Target cNFs must be located on the subject's face, anterior trunk, or upper extremities. Two Target cNFs must be on the face and 8 must be on the anterior trunk or upper extremities. The study medication will be applied topically QD to the Target cNFs for 182days (26 weeks). During the duration of the study subjects will be evaluated for safety and efficacy.

Condition Cutaneous Neurofibroma, Neurofibromatosis 1
Treatment Vehicle gel, NFX-179 Gel
Clinical Study IdentifierNCT05005845
SponsorNFlection Therapeutics, Inc.
Last Modified on30 March 2023

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