Intravenous Oliceridine and Opioid-related Complications
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- STATUS
- Recruiting
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- End date
- Jul 15, 2025
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- participants needed
- 200
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- sponsor
- The Cleveland Clinic
Summary
The investigator will evaluate the side effects of oliceridine.
Description
The investigator will evaluate the side effects of oliceridine. Limited information suggests that oliceridine may cause fewer side effects than the standard opioids given post surgery. Oliceridine is effective for treating acute pain, and is approved by the FDA. Patients will wear a device that continuously monitors breathing. Data from this monitor will be blinded to the clinical staff. Primary Aims include: The investigators will evaluate the proportion of patients having an adjudicated meaningful respiratory compromise with a specified precision of 0.15 using a 95% confidence interval at 24 hours post first study dose.
Details
| Condition | Major Surgery |
|---|---|
| Treatment | Oliceridine |
| Clinical Study Identifier | NCT04979247 |
| Sponsor | The Cleveland Clinic |
| Last Modified on | 25 April 2022 |
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