OFA in Thoracic Surgery
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- STATUS
- Recruiting
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- End date
- Dec 1, 2025
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- participants needed
- 60
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- sponsor
- Shanghai Zhongshan Hospital
Summary
to investigate the efficacy and safety of opioid-free anesthesia for non-small-cell lung cancer resection and its underlying clinical value
Description
Opioids used to have its irreplaceable role in standard opioid-based anesthesia, yet with the help of hypnotics, local anesthetics, anti-inflammatory drugs, α-2 agonists and epidural techniques, opioid-free anesthesia (OFA) has been proved to be safe and feasible for non-cardiac major surgeries. Opioid-sparing anesthesia (OSA) is encouraged by the needs of enhanced recovery and recommended by the latest guidelines for anesthesia of lung surgery. According to previous studies, both opioid-sparing and opioid-free anesthesia would reduce the incidence of opioid-related adverse events and speed up the postoperative recovery to some extent, yet no studies ever are dedicated to compare these two different techniques.
Details
| Condition | Thoracic Cancer |
|---|---|
| Treatment | opioid free anesthesia, Opioid-sparing anesthesia |
| Clinical Study Identifier | NCT05063396 |
| Sponsor | Shanghai Zhongshan Hospital |
| Last Modified on | 15 May 2022 |
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