Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism

  • STATUS
    Recruiting
  • End date
    May 31, 2028
  • participants needed
    200
  • sponsor
    The Second Hospital of Nanjing Medical University
Updated on 4 October 2021

Summary

Total parathyroidectomy with autotransplantation (TPTX+AT) and Total parathyr- oidectomy alone (TPTX) are the common surgical procedures.The purpose of the study was to compare the long-term benefits of surgery between the two groups.

Description

The trial was performed as a nonconfirmatory randomized controlled pilot trial with 200 patients on long-term dialysis with otherwise uncontrollable SHPT to generate data on the rate of recurrent disease within a 5-year follow-up period after TPTX or TPTX+AT. Parathyroid hormone (PTH) and calcium levels, recurrent or persistent hyperparathyroidism, parathyroid reoperations, morbidity, and mortality were evaluated during a 5-year follow-up.

Details
Condition Secondary Hyperparathyroidism;Parathyroidectomy
Treatment parathyroidectomy
Clinical Study IdentifierNCT04922892
SponsorThe Second Hospital of Nanjing Medical University
Last Modified on4 October 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Severe renal secondary hyperparathyroidism

Exclusion Criteria

Patients with diabetes a history of chronic inflammatory disease a history of
malignant tumor a history of kidney transplantation a history of neck surgery
a history of alcohol abuse a history of drug abuse inability to cooperate with
the participants refusal to participate in the study
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