Body Weight Growth After Birth and Bronchopulmonary Dysplasia

  • STATUS
    Recruiting
  • End date
    Dec 31, 2022
  • participants needed
    200
  • sponsor
    Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Updated on 1 October 2021

Summary

Bronchopulmonary dysplasia (BPD) is one of the most common, complex, and severe diseases in preterm infants. BPD was first described as chronic pulmonary disease in survivors of severe respiratory distress syndrome (RDS) in 1967, which was also called as the "old" BPD. In recent years, the definition for BPD has developed a lot. The National Institute of Child Health and Human Development (NICHD) workshop in 2018 assessed BPD at 36 post-menstrual age (PMA) along with radiographic confirmation and used a severity grading of I-III. Although with effective surfactant supplement and oxygen support, BPD brings a great challenge to neonatologists.

Description

Besides persistent inflammation, prolonged invasive ventilation and oxidative damage. body weight is the one of the most important factors to induce BPD. Poor extrauterine growth is commonly described in extremely preterm infants. But, the relationship of postnatal growth with BPD and respiratory morbidity is not entirely understood.

The aim of the present study is to assess whether body weight growth after birth is the risk factor for BPD.

Details
Condition Bronchopulmonary Dysplasia, Preterm, bronchopulmonary dysplasia (bpd)
Treatment good body weight growth, poor body weight growth
Clinical Study IdentifierNCT05053269
SponsorDaping Hospital and the Research Institute of Surgery of the Third Military Medical University
Last Modified on1 October 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

equal to or less than 32 weeks' gestational age

Exclusion Criteria

main congenital malformation
parents' refusal
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