Safety and Efficacy of Curcumin in Children With Acute Lymphoblastic Leukemia

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    Ain Shams University
Updated on 24 September 2021


Assessment of of the biological effects of curcumin on microbiota in children with acute lymphoblastic leukemia


Assessment of the safety of curcumin, which is the most active constituent of the ground rhizome of the Curcuma longa plant, in children with acute lymphoblastic leukemia patients (ALL) in maintenance phase of chemotherapy through the assessment of the any reported adverse event (AE). And assessment of the curcumin effect on health by eliminating intestinal microflora dysbiosis

Condition Lymphocytic Leukemia, Acute, childhood ALL
Treatment Standard of Care, Curcumin
Clinical Study IdentifierNCT05045443
SponsorAin Shams University
Last Modified on24 September 2021


Yes No Not Sure

Inclusion Criteria

Children aged from 1 year to 18 years Children with proven ALL diagnosed by
bone marrow aspirate and immunephenotyping Patients in the maintenance phase

Exclusion Criteria

Children with other maliganacies, Current use (past use of these medications
is not an exclusion) of medications or over-the-counter treatments including
to sulfasalazine, warfarin, clopidogrel, aspirin, antacids, botanical
treatments (ginger, feverfew, yellow clover, Salix species, Populus species
Betula species, and Gaultheria species), essential fatty acids (flax oil and
fish oil)
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