Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea

  • End date
    Aug 4, 2023
  • participants needed
  • sponsor
    Chang Gung Memorial Hospital
Updated on 29 September 2021


The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.


Rosacea is a chronic inflammatory disorder which affects the cheek, nose, chin, forehead and eyes. It is typically characterized by cutaneous signs such as flushing, erythema, telangiectasia, papules, and pustules in the face. The pathogenic mechanism of rosacea is unknown, and there is no cure for rosacea. The therapeutic approaches include oral medicine, topical medicine and surgical interventions depending on the different subtypes of rosacea. The recent study demonstrates that combination therapy may be more effectively improved the symptoms of rosacea. Dian dao san is a topical herbal compound for reducing the features as flushing, erythema, papules, and pustules for years. The investigators hypothesize that dian dao san can be more beneficial in treating the patients with rosacea and improving the quality of life.

Condition Skin Conditions, Dermatosis, Rosacea, Chinese Herbal Medicine, Rosacea, Topical Herbal Medicine, Congenital Skin Diseases, chinese herbal medicines
Treatment dian dao san
Clinical Study IdentifierNCT05045469
SponsorChang Gung Memorial Hospital
Last Modified on29 September 2021


Yes No Not Sure

Inclusion Criteria

Willing to sign inform consent
Aged above 20 years old with rosacea
No treatment for rosacea within 2 weeks

Exclusion Criteria

With malignant lesion in the rosacea lesion
Rosacea lesion with high risk of infection
Allergy to Chinese herbal medicine patch or ointment
Clear my responses

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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