Catch me if You Can - the Individual Relationship Between Potential Ablation Targets From CARTOFINDER and Myocardial Fibrosis

  • STATUS
    Recruiting
  • End date
    Mar 1, 2023
  • participants needed
    20
  • sponsor
    Heart and Diabetes Center North-Rhine Westfalia
Updated on 19 September 2021
fibrillation
persistent atrial fibrillation

Summary

Single center observational study to compare the relationship between atrial fibrosis and potential ablation targets from CARTOFINDER.

Description

A total number of 30 patients will undergo catheter Ablation for persistent AF. Pre-procedural cardiac MRI will be performed with late-gadolinium enhancement to visualize the individual amount and distribution of fibrosis in the right and left atrium. CARTOFINDER-guided mapping will be performed during the ablation procedure followed by AF ablation. The individual relationship between atrial fibrosis and potential ablation targets will be accessed.

Details
Condition Atrial Fibrillation (Pediatric), Dysrhythmia, Atrial Fibrillation, Arrhythmia
Clinical Study IdentifierNCT04586881
SponsorHeart and Diabetes Center North-Rhine Westfalia
Last Modified on19 September 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients undergoing their 1st AF ablation procedure for persistent atrial fibrillation (AF) as per recent Heart Rhythm Society (HRS) consensus document
Able to understand and willing to sign the Informed Consent Form
Age 18 years

Exclusion Criteria

Contraindication for DE-MRI with a full dose of Gadolinium-based contrast agent
Previous left atrial ablation or surgical procedure
Renal failure with CrCl <60 ml/min
Women currently pregnant, breastfeeding, or of childbearing age not currently taking or not willing to use a reliable form of contraception
Mental or physical inability to take part in the study
Uncontrolled hypertension
Morbid obesity (BMI > 35), or inability to be placed in MRI due to body mass
Clear my responses

How to participate?

Step 1 Connect with a study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

0/250

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Loading...

Browse trials for

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer

user name

Added by • 

 • 

Private

Reply by • Private
Loading...

Lorem ipsum dolor sit amet consectetur, adipisicing elit. Ipsa vel nobis alias. Quae eveniet velit voluptate quo doloribus maxime et dicta in sequi, corporis quod. Ea, dolor eius? Dolore, vel!

  The passcode will expire in None.
Loading...

No annotations made yet

Add a private note
  • abc Select a piece of text from the left.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.
Add a private note