Tablet-based Cognitive Training
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- STATUS
- Recruiting
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- End date
- Apr 1, 2025
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- participants needed
- 162
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- sponsor
- University of Bern
Summary
Today the therapy options for dementia due to Alzheimer's disease (AD) are limited. One recommended intervention is cognitive stimulation. We try to develop serious games as a further treatment option, also usable in pre-dementia as well as early stages of dementia and for a long period of time.
The main objective of this study is to test, if the computerized-cognitive training (CCT) is able to improve the performance in a score quantifying an "AD-specific" component score. Additionally, the neurobiological effects of the training are investigated.
Description
The study intervention consists of a computer-based cognitive training, targeting the cognitive domains mostly affected by AD. This training will be performed for three months (each day for 20 minutes). After three months the intervention group will continue the training at home for six months and meet monthly for group sessions (i.e. booster sessions) on site.
Primary endpoint will be the change in an "AD-specific" component score, quantified by episodic memory, semantic memory and visuospatial abilities. Secondary endpoints are changes in task related brain networks and changes in resting state networks.
Details
| Condition | Alzheimer Disease, Dementia, Mild Cognitive Impairment |
|---|---|
| Treatment | computerized cognitive training, Documentaries with delayed Computerized Cognitive Training |
| Clinical Study Identifier | NCT04452864 |
| Sponsor | University of Bern |
| Last Modified on | 25 January 2022 |
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