The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS

  • End date
    Dec 30, 2022
  • participants needed
  • sponsor
    Huazhong University of Science and Technology
Updated on 30 April 2022
postoperative pain
nerve block
paravertebral block


Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia. This study is to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.


Ultrasound-guided nerve block is an important part of multi-mode analgesia to decrease the consumption of opioids. Thoracic paravertebral block is considered as an ideal regional analgesic choice for video-assisted thoracic surgery, but it still has some side effects, such as pneumothorax, vascular injury, especially for novices. Recent years, ultrasound-guided mid-point transverse process to pleura block and erector spinae plane block are reported for thoracic surgery. The insertion depth in these two methods is more superficial than traditional paravertebral block. They could have less side effects. Therefore, we design a randomised control study to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.

Condition Thoracic Anesthesia, Nerve Block, Pain, Acute
Treatment paravertebral block, ESP block, MTP block
Clinical Study IdentifierNCT04829409
SponsorHuazhong University of Science and Technology
Last Modified on30 April 2022


Yes No Not Sure

Inclusion Criteria

selective lobetomy under VATS
ASA classfication 1-3

Exclusion Criteria

history of thoracic surgery
double lateral VATS
allergy to local anesthetics
coagulation disorders
severe heart diseases, hepatic or renal insufficiency
a history of chronic pain or chronic opioid use
psychiatric disease or uncooperative
BMI>28 kg/m2
VATS transfered to open thoractomy
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