Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients (CapnoGI)

  • End date
    Dec 5, 2023
  • participants needed
  • sponsor
    RenJi Hospital
Updated on 5 April 2022
Accepts healthy volunteers


Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol and sufentanil, especially in elderly people. The aim of this randomized study was to determine whether intervention based on additional capnographic monitoring reduces the incidence of hypoxia in gastrointestinal endoscopes procedures for elderly patients.

Condition Hypoxia, Gastric Cancer, Gastric Polyp, Colon Polyp, Colon Cancer, Esophageal Cancer
Treatment Capnography monitoring, Standard monitoring
Clinical Study IdentifierNCT05030870
SponsorRenJi Hospital
Last Modified on5 April 2022


Yes No Not Sure

Inclusion Criteria

≤ Age <80
patients undergoing gastrointestinal endoscopes
patients signed informed consent form
ASA classification I-II

Exclusion Criteria

Coagulation disorders or a tendency of nose bleeding
An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months
Severe aortic stenosis or mitral stenosis
Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months
Acute myocardial infarction in the last 6 months
Acute arrhythmia (including any tachycardia - or bradycardia) with the fluid of hemodynamics instability
Diagnosed chronic obstructive pulmonary disease or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy)
Pre-existing bradycardia (heart rate < 50 / min), or hypoxia (SaO2< 90 % )
Need supplemental oxygen because of pre-existing diseases
Emergency procedure or surgery
Multiple trauma
Upper respiratory tract infection
Allergy to propofol or tape and adhesives
Clear my responses

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