A Clinical Trial of GSK3640254 + Dolutegravir (DTG) in Human Immunodeficiency Virus-1 Infected Treatment-naive Adults (DYNAMIC)

    Not Recruiting
  • End date
    May 24, 2023
  • participants needed
  • sponsor
    ViiV Healthcare
Updated on 20 July 2022
body mass index
HIV Vaccine
hiv-1 rna measurement


The purpose of this study is to evaluate the efficacy of GSK3640254 + DTG relative to lamivudine (3TC) + DTG in treatment-naïve adult participants living with human immunodeficiency virus (HIV)-1. The participants will be randomized to one of the three doses of blinded GSK3640254 (100, 150, or 200 milligrams [mgs]) or a reference arm of blinded 3TC-each in combination with open label DTG.

Condition HIV Infections
Treatment dolutegravir, GSK3640254, Lamivudine capsules, Lamivudine tablets
Clinical Study IdentifierNCT04900038
SponsorViiV Healthcare
Last Modified on20 July 2022

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