Meal Delivery and Exercise

  • End date
    Feb 28, 2026
  • participants needed
  • sponsor
    The University of Texas Health Science Center, Houston
Updated on 24 December 2021


The purpose of this study is to evaluate the effects of a home-based exercise program administered through Meals on wheels (MOW) on gait speed and frailty status and to assess the association between novel serum biomarkers (70 kilodalton heat shock proteins (HSP70),Macrophage Inflammatory Proteins(MIP1b), soluble IL-6 receptor alpha-chain (sIL-6R)) and established but non-specific frailty biomarkers (Interleukin 6 (IL-6), C-reactive protein (CRP), Tumor necrosis factor (TNF-α)) in frail and prefrail homebound older adults before and after the exercise intervention.

Condition Frailty
Treatment Meals plus exercise, Meals only
Clinical Study IdentifierNCT04906759
SponsorThe University of Texas Health Science Center, Houston
Last Modified on24 December 2021


Yes No Not Sure

Inclusion Criteria

enrolled in the UTHealth-Harris Health House Call Service (HCS)
frail or prefrail by The Fried Frailty Phenotype (FFP)
medically stable

Exclusion Criteria

robust by FFP
have Mini-Cog score <3 and/or are unable to follow instructions
have a pre-diagnosed terminal illness
unable to ambulate
unable to use their upper extremities, and/or are already participating in physician-prescribed physical therapy or occupational therapy
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