Dose Efficiency of Modern CT Scanners in Oncologic Scans

  • End date
    Aug 17, 2023
  • participants needed
  • sponsor
    University Hospital Augsburg
Updated on 26 August 2021
primary cancer


CT-Staging is crucial for therapy planning of patients with malignancies. Dose efficiency and image quality are important parameters for these examinations. Up to now, scientific evidence of dose efficiency of modern CT scanners is mostly derived from retrospective analyses. This prospective study systematically analyzes dose efficiency and image quality of three modern CT scanners by randomization of patients who are scheduled for a CT scan to examine the status of malignancies. After giving informed consent and randomization (1:1:1), the CT scan will be performed at one of the modern CT scanners available at our department. This will allow a systematic allocation to the different scanners.

Condition Neoplasm Metastasis, cancers metastatic, Cancer, Metastatic, Brain Metastases, Cancer (Pediatric), Cancer/Tumors, Cancer, metastatic disease, Metastatic Cancer, secondary cancer, metastases, metastatic tumor, Ewing's Family Tumors, Metastasis, secondaries, Neoplasms, metastasized, Liver Metastases, Bone Metastases
Treatment Scan at CT scanner 1, Scan at CT scanner 2, Scan at CT scanner 3
Clinical Study IdentifierNCT04989192
SponsorUniversity Hospital Augsburg
Last Modified on26 August 2021


Yes No Not Sure

Inclusion Criteria

clinical suspicion of a malignancy or known / confirmed malignancy AND
indication for contrast-enhanced CT of the body confirmed by board-certified radiologist ('justifying indication' according to German/European radiation protection law) AND
patient (is able to give informed consent and) has given informed consent

Exclusion Criteria

age < 18 years
known or suspected pregnancy
contraindications for contrast agent (renal failure, allergy, hyperthyroidism)
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