A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of MK-4482 for the Prevention of COVID-19 (Laboratory-confirmed SARS-CoV-2 Infection With Symptoms) in Adults Residing With a Person With COVID-19 (MOVe-AHEAD)

  • STATUS
    Recruiting
  • participants needed
    1376
  • sponsor
    Merck Sharp & Dohme LLC
Updated on 28 January 2023
Accepts healthy volunteers

Summary

The purpose of the study is to assess if the study medication (molnupiravir, MK-4482) will prevent symptomatic coronavirus disease 2019 (COVID-19) in adults who live with someone with confirmed COVID-19 infection. This is a phase 3, multicenter, randomized, double-blind, placebo-controlled study; half of the study participants will receive molnupiravir twice daily by mouth and the other half will receive a placebo. The primary objectives of the study are to determine if molnupiravir prevents symptomatic COVID-19 disease and to evaluate its safety and tolerability. All participants who develop COVID-19 during the study are still eligible for any COVID-19 treatment recommended by their doctor.

Details
Condition Coronavirus Disease (COVID-19)
Treatment Placebo, Molnupiravir
Clinical Study IdentifierNCT04939428
SponsorMerck Sharp & Dohme LLC
Last Modified on28 January 2023

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