Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity

  • STATUS
    Recruiting
  • End date
    Mar 23, 2023
  • participants needed
    62
  • sponsor
    Aya Sabry Mohamed Mohamed
Updated on 23 August 2021

Summary

Intravenous lipid emulsion is an established, effective treatment for local anesthetic systemic toxicity. It is also efficacious in animal models of severe cardiotoxicity caused by a number of other medications. Recent case reports of successful resuscitation suggest the efficacy of lipid emulsion infusion for treating non-local anesthetic overdoses across a wide spectrum of drugs. The present study will focus on the potential role of intravenous lipid emulsion as an adjuvant therapy in pesticides toxicity.

Details
Condition Pesticide Poisoning
Treatment atropine, Lipid Emulsion, Intravenous, Toxogonin, Sodium Bicarbonate Powder and ondansetron
Clinical Study IdentifierNCT05006638
SponsorAya Sabry Mohamed Mohamed
Last Modified on23 August 2021

Eligibility

Yes No Not Sure

Inclusion Criteria

Patients with acute pesticide intoxications with poison severity score 2 or 3 admitted in ICU of PCC-ASUH

Exclusion Criteria

Patients less than 18 years and more than 65 years
Pregnant and lactating females
Presence of medical diseases (e.g. renal, hepatic, cardiovascular, neurological diseases and chronic pancreatitis.)
Allergy to soya-, egg-or peanut protein
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