Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity

  • End date
    Mar 23, 2023
  • participants needed
  • sponsor
    Aya Sabry Mohamed Mohamed
Updated on 4 October 2022


Intravenous lipid emulsion is an established, effective treatment for local anesthetic systemic toxicity. It is also efficacious in animal models of severe cardiotoxicity caused by a number of other medications. Recent case reports of successful resuscitation suggest the efficacy of lipid emulsion infusion for treating non-local anesthetic overdoses across a wide spectrum of drugs. The present study will focus on the potential role of intravenous lipid emulsion as an adjuvant therapy in pesticides toxicity.

Condition Pesticide Poisoning
Treatment atropine, Lipid Emulsion, Intravenous, Toxogonin, Sodium Bicarbonate Powder and ondansetron
Clinical Study IdentifierNCT05006638
SponsorAya Sabry Mohamed Mohamed
Last Modified on4 October 2022


Yes No Not Sure

Inclusion Criteria

Patients with acute pesticide intoxications with poison severity score 2 or 3 admitted in ICU of PCC-ASUH

Exclusion Criteria

Patients less than 18 years and more than 65 years
Pregnant and lactating females
Presence of medical diseases (e.g. renal, hepatic, cardiovascular, neurological diseases and chronic pancreatitis.)
Allergy to soya-, egg-or peanut protein
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