Verification of the Efficacy/Safety of the Dual Drug Delivery for Hearing Loss

  • days left to enroll
  • participants needed
  • sponsor
    Seoul National University Hospital
Updated on 22 August 2021


This study is a prospective, randomized pilot study. To verify an efficacy and safety of the dual drug injectable delivery vehicle, patients who have not responded to the existing standard treatment will be enrolled. Hearing test and endoscopy of tympanic membrane will be conducted after intratympanic treatment for evaluation.

Condition Sudden hearing loss, Meniere's Disease, Acoustic Trauma, noise-induced hearing loss, Hearing Loss Ototoxic
Treatment Dexamethasone, Hyaluronic Acid
Clinical Study IdentifierNCT04766853
SponsorSeoul National University Hospital
Last Modified on22 August 2021


Yes No Not Sure

Inclusion Criteria

Sudden hearing loss, ototoxic hearing loss, noise-induced hearing loss, meniere's disease patients with 25dB HL in pure tone audiometry
Patients whose hearing has not been restored after standard treatment
Patients do not participate in clinical trials within 6 months

Exclusion Criteria

Patients with retrocochlear lesion
Patients with history of hypersensitivity to the substance of this drug
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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