Effect of EPAP Device on Emphysema and Lung Bullae

  • participants needed
  • sponsor
    Qilu Hospital of Shandong University
Updated on 30 November 2022


The purpose of this study is to evaluate the safety and the effects and of the application of Expiratory Positive Airway Pressure (EPAP) device on Dynamic Hyperinflation and dyspnea in patients with Emphysema and pulmonary bullae.


The trial will last for six months. Patients will be collected clinical and anthropometric data by using questionnaires initially. Patients will have the pulmonary function test and CT scan and conduct 6MWT every two months. And Borg scale data will be collected every two months. The application of EPAP (15cmH2O) via face mask will be randomized with the help of opaque envelopes.

Condition Emphysema, Bullous Disease Lung
Treatment use the face mask with Expiratory Positive Airway Pressure(EPAP)., use the face mask without Expiratory Positive Airway Pressure(EPAP).
Clinical Study IdentifierNCT04742114
SponsorQilu Hospital of Shandong University
Last Modified on30 November 2022

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