A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)

  • STATUS
    Recruiting
  • participants needed
    6
  • sponsor
    Global Blood Therapeutics
Updated on 6 July 2022
hemoglobin s
sickle hemoglobin

Summary

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK), and pharmacodynamics (i.e., how the body absorbs, distributes, breaks down, and excretes) of GBT021601, a hemoglobin S (HbS) polymerization inhibitor, in participants with SCD, following single and multiple ascending doses.

Description

This is an open-label intrapatient single dose followed by a multiple dose escalation study in at least six (6) participants with SCD.

Details
Condition Sickle Cell Disease
Treatment GBT021601
Clinical Study IdentifierNCT04983264
SponsorGlobal Blood Therapeutics
Last Modified on6 July 2022

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