Mirror Therapy Rehabilitation for Motor Functional Neurological Disorders.

  • End date
    Jun 8, 2024
  • participants needed
  • sponsor
    Hospices Civils de Lyon
Updated on 8 August 2021


Motor functional neurological disorders (FND) correspond to motor symptoms that are unexplained by an organic lesion but are due to cerebral dysfunction. Patients with these disorders have high rates of disability and health care utilization, and their quality of life is as impaired as that of patients with an "organic" disease. Accompanying these patients in their often-complex health journey represents a socio-economic and human challenge that demands interdisciplinary collaboration. Rehabilitation is seen as an important part of the therapy for motor FND. However, further research is needed to refine appropriate interventions and to create evidence-based recommendations. In this study, patients suffering from a functional neurological motor disorder of the upper limb will be included in a novel rehabilitation protocol that includes computerized mirror therapy. The study will used a multiple baseline, across subjects, single-case experimental design (SCED). In this type of design, each subject is his own control, with individual parameters being repeatedly measured in the presence and absence of the intervention of interest (computerized mirror therapy). Computerized mirror therapy could restore the coherence between the motor program and its execution. The investigators hypothesize that this process could re-normalize upper-limb motor activity and that this will have a beneficial impact on manual dexterity, quality of life, and mental representation capacities of the upper limb.

The objective of this project is to use the single case experimental design method to investigate the efficacy of rehabilitation with computerized mirror therapy for patients suffering from motor neurological disorders (FND) of the upper limb.

Condition Functional Neurological Symptom Disorder
Treatment One-on-one rehabilitation program including computerized mirror therapy in addition to standard rehabilitation.
Clinical Study IdentifierNCT04739176
SponsorHospices Civils de Lyon
Last Modified on8 August 2021


Yes No Not Sure

Inclusion Criteria

Age 18 years old
Included in the PULSES program (University Program of Liaison and Care for Somatoform Etiologies)
Announcement and explanation of the diagnosis already given to the patient
Motivated to participate in the project
Diagnosed with any type of motor functional neurological disorder : partial or complete deficits and abnormal movements
With a lateralized disorder (limited to one hemi-body) involving at least the upper limb
Disorder must primarily involve the distal part of the upper-limb (fingers, wrist)
Admitted to the day hospital at Henry Gabrielle Hospital during the study
Given free, informed consent in writing after being informed orally and in writing of how the study will proceed

Exclusion Criteria

Patients with visual disorders such as uncorrected diplopia, blindness or low visual acuity (corrected or uncorrected)
Pregnant, parturient and breastfeeding women
Patients under a legal protection measure such as guardianship or curatorship
Patients not affiliated to a social security scheme (French Social Security) or beneficiaries of a similar scheme
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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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