ATR Inhibitor BAY 1895344 plus pembrolizumab in advanced solid tumors (GI, Pancreatic, mCRPC, NSCLC)

    Not Recruiting
  • sponsor
Updated on 16 August 2022
measurable disease


This clinical study aims to investigate if impairment of the deoxyribonucleic acid damage repair (DDR) pathway by the Elimusertib in combination with blockade of the PD-1/PD-L1 pathway by pembrolizumab, may improve antitumor responses in advanced cancer patients with DDR aberrations, at an acceptable safety profile and an expected positive benefit/risk ratio.


Condition Gastric Cancer, solid tumors, Pancreatic cancer, CRPC, nsclc, solid tumor, mCRPC, Pancreatic Cancer, Prostate Cancer, Lung cancer, Islet Ce417ll Cancer, oncology, NSCLC, Prostate cancer, ATR, Stomach Cancer, GI cancer
Clinical Study IdentifierTX279019
Last Modified on16 August 2022

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