Effect of MEMOPTIC on Visual Field of Patients Followed for a Chronic Open-angle Glaucoma

  • days left to enroll
  • participants needed
  • sponsor
    Centre Hospitalier Universitaire, Amiens
Updated on 31 July 2021
brimonidine tartrate ophthalmic solution
treatment of glaucoma


Open-angle glaucoma is a degeneration of the optic nerve, highlighted by campimetric alterations, and wose only current therapeutic target is the lowering of the intra-ocular pressure (using eye drops, surgery or laser). MEMOPTIC is a tablet combining citicoline, magnesium and Gingko biloba, which have a neuroprotective effect already used in neurodegenerative diseases such as Alzheimer's disease for example. Citicoline has also shown several promising results in ophthalmological diseases (glaucoma, amblyopia or more recently in ischemic optic neuropathies). The citicoline used in eye drops (NEURODROP) has already shown results on the preservation of the vision of glaucomatous patients.

The purpose of this project is to determine if MEMOPTIC can have an effect, in addition to the conventional treatments, in the preservation of vision of patients treated for an open-angle glaucoma.

Condition Open Angle Glaucoma, Visual field, Glaucoma, Pigmentary glaucoma
Treatment MEMOPTIC, usual treatment of glaucoma
Clinical Study IdentifierNCT04499157
SponsorCentre Hospitalier Universitaire, Amiens
Last Modified on31 July 2021


Yes No Not Sure

Inclusion Criteria

diagnosis of GCAO defined by OCT RNFL alterations and visual fields defects
age between 20 and 80 years old
Well controled intra-ocular pressure under treatment (PIO<21mmHg or decreased by 20% compared to initial the PIO)

Exclusion Criteria

retinal or macular disease
diagnosis of cataract or surgery of cataract during the follow-up
allergy to citicolin
ocular hypertonia due to a secondary cause (like corticosteroids)
history of anterior, intermediate or posterior uveitis
general treatment affecting PIO (beta blockers, corticosteroids)
pregnancy or breastfeeding
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